Robitussin is a registered trademark and trademark for cough free and over-the-counter and prescription-free medicines manufactured by Pfizer. Robitussin products are available in many countries around the world, although formulation and regulatory standards vary across countries. Robitussin was produced at Darbytown Road in Richmond, Virginia, on a site once owned by drug developer, AH Robins; generic version made by Qualitest.
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Histori
Robitussin was originally produced by AH Robins of Richmond, Virginia. AH Robins was purchased by American Home Products (AHP) in the late 1980s. AHP then joined Wyeth. Wyeth puts its manufacturing and brand marketing under the Whitehall-Robins Healthcare division. Production was taken over by Pfizer when it acquired Wyeth in 2009.
During the 1970s and early 1980s, Merrell Dow Pharmaceuticals sold the same cough syrup (slightly different in taste, but pharmacologically identical) under the name "2/G" (reference to "glyceryl guaiacolate," the old name for guaifenesin ) for the expectorant base formulation and "2G/DM" for guaifenesin/dextromethorphan formulations.
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Summary of active ingredients
The Robitussin brand name is used for some formulations of cough and cold medicines that contain different active ingredients:
- Acetaminophen
- Acetaminophen is an analgesic (pain reliever) and an antipyretic (fever damp) found in some formulations of Robitussin CF, as well as Cold Daytime Flu pills.
- Codeine (phosphate)
- Codeine is an antitussive narcotics found in Robitussin DAC and Robitussin AC. In the United States, codified cough formulations are usually only prescriptions, but the degree of regulation may vary from state to state.
- Chlorpheniramine (maleate)
- Chlorpheniramine is an antihistamine found in various cough and cold medicines of children.
- Dextromethorphan (hydrobromide)
- Dextromethorphan is antitussive, with a dissociative effect, found in most OTC Robitussin products.
- Diphenhydramine (hydrochloride)
- Diphenhydramine is an antihistamine found in some formulations of Robitussin at night.
- Doxylamine (succinate)
- Doxylamine is a sleep aid found in some nightly Robitussin formulations.
- Guaifenesin
- Guaifenesin is an expectorant found in most Robitussin products designed to relieve cough and chest congestion.
- Menthol
- Menthol is an oral anesthetic found in Robitussin DM lozenges.
- Phenylephrine (hydrochloride)
- Phenylephrine is a decongestant found in Robitussin CF and Cold Cold Flu Daytime.
- Promethazine (hydrochloride)
- Promethazine is an antihistamine found in Robitussin formulations at night that is older. Like codeine, it's just a recipe in the US.
- Pseudoephedrine (hydrochloride)
- Pseudoephedrine is a decongestant that has largely been replaced by phenylephrine in the Robitussin OTC formulation, although it may still be available in syrup recipes.
Robitussin DAC/Robitussin AC
Robitussin DAC is used to treat acute cough, mucus buildup and nasal congestion. Because this drug contains codeine, it is usually only prescribed when the patient has a painful and persistent cough, and/or that interrupts the patient's sleep cycle. Every 5 mL of Robitussin DAC contains 10 mg of codeine, 100 mg guaifenesin, and 30 mg of pseudoephedrine.
Robitussin AC is Robitussin DAC without pseudoephedrine. The taste of imitating the cherry but is said to have a sense after the unpleasant. Robitussin AC versions with promethazine are usually given a peach-mint or grape/menthol flavor. This syrup is purple, not red. Robitussin AC has a 3.5% alcohol content, and the version with promethazine contains 7% alcohol.
The generic form is available under the name Cheratussin DAC and Cheratussin AC.
External links
- Walgreens Drug information site for Cheratussin DAC
- List of Drugs.com drugs for Robitussin DAC
- McGraw-Hill Pharmacy Access Pharmacy and Federal Drug Law Review
- Robitussin product line
Source of the article : Wikipedia
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